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First published in 1978, This book was immediately recognized as a revolutionary approach to the field of embryology. In a dramatic departure form traditional concepts of human differentiation, the authors refute Haeckel's biogenetic law ("ontogeny recapitulates phylogeny") and instead show how the ovum is distinctly human at every stage of its development. In addition, the developing embryo is viewed as a single unity rather than as a number of isolated parts, and differentiations are seen as dynamic processes that result directly from extra-genetic information - proceeding from the outside to the inside, not the inside to the outside according to genetic patterning.
Fifty years ago the field of human embryology was incomplete; prior to that time the anatomy of early human embryos was still unknown, and there was much to be learned about the older stages of human embryonic development. It is now understood that human organs result from step-by-step differentiations of the growing human embryo. Research by renowned embryologist Erich Blechschmidt, MD, showed that differentiations are not only the result of a gene effect, but are also brought about through growth initiated by extragenetic (occurring outside the gene) information. Without this extragenetic information the differentiation would not begin.
Dr. Blechschmidt and coauthor Raymond Gasser, PhD, maintain that Haeckel's biogenetic law (ontogeny recapitulates phylogeny) was an erroneous attempt to explain developmental processes. Blechschmidt's human embryological investigations showed that Darwin's principles (mutation and selection) are likely valid for the origin of the species, but that they cannot explain the ontogenesis of the organs. The ontogenesis of each individual cannot be derived from phylogenetic facts. The authors stress that a clear distinction must be made between the vast field of phylogenetics and the much more exact and understandable field of ontogenetics—particularly the process of differentiation—and their goal is to present not only the abstract biokinetic principles of differentiation, but the originality of embryonic human beings as well. Their knowledge of developmental movements leads to their conclusion that differentiation is an undivided biodynamic process that occurs during development and includes the chemical processes as well.
Logically organized into two sections (the first covers early metabolic fields and includes chapters on the one-cell human ovum, the early embryo, blood vessels, the nervous system, head region, trunk, and limbs; the second describes metabolic fields in later developmental stages, distinguishing fields of corrosion, densation, contusion, distusion, retention, dilation, liquation, and detraction), Biokinetics and Biodynamics of Human Differentiation warrants reading by thoughtful professionals in a number of fields concerned with embryonic differentiation. A new preface by Dr. Gasser addresses how the book's principles and findings were and are understood in the field of human embryology.
Erich Blechschmidt, M.D. (1904 - 1992) was a well-known and extremely progressive anatomist and embryologist who studied the human form and the way it develops during ontogeny, principally during the first eight weeks after conception. He is the author of more than 120 scientific papers and numerous book, including "The Ontogenetic Basis of Human Anatomy".
Raymond Frank Gasser, MS, PhD. is Professor Emeritus of Clinical Anatomy at the Louisiana State University School of Medicine in New Orleans. He also is a member of the Federative international Committee for Anatomical Terminology and the Advisory Committee for the Human Developmental Anatomy Center of the Armed Forces Institute of Pathology in Washington, DC. His recent research consists of computer imaging and storage of human embryo section images in databases at each Carnegie stage on CDs and DVDs for distribution to developmental biologist, human embryology authors, lecturers and students. He resides in Covington, Louisiana.